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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 2
1947 1
1949 1
1950 1
1953 1
1954 2
1956 2
1957 3
1958 3
1963 1
1964 1
1965 1
1966 3
1967 4
1968 2
1969 4
1970 4
1971 2
1973 2
1974 4
1975 26
1976 29
1977 22
1978 27
1979 31
1980 29
1981 18
1982 38
1983 42
1984 34
1985 53
1986 79
1987 106
1988 123
1989 131
1990 132
1991 141
1992 118
1993 125
1994 124
1995 104
1996 138
1997 121
1998 113
1999 123
2000 133
2001 138
2002 115
2003 128
2004 139
2005 158
2006 164
2007 183
2008 180
2009 166
2010 183
2011 184
2012 186
2013 246
2014 216
2015 236
2016 274
2017 251
2018 260
2019 293
2020 314
2021 297
2022 293
2023 280
2024 125

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6,648 results

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Page 1
Over par.
Meyer CR. Meyer CR. Minn Med. 2000 Nov;83(11):2. Minn Med. 2000. PMID: 11126474 No abstract available.
Over-expression of PAR-3 suppresses contact-mediated inhibition of cell migration in MDCK cells.
Mishima A, Suzuki A, Enaka M, Hirose T, Mizuno K, Ohnishi T, Mohri H, Ishigatsubo Y, Ohno S. Mishima A, et al. Genes Cells. 2002 Jun;7(6):581-96. doi: 10.1046/j.1365-2443.2002.00540.x. Genes Cells. 2002. PMID: 12059961 Free article.
BACKGROUND: PAR-3 is one of the PAR proteins, previously named ASIP, which are indispensable for the establishment of cell polarity in the embryo as well as differentiated epithelial cells. ...RESULTS: To gain insights into the mode of PAR-3 function in mamma …
BACKGROUND: PAR-3 is one of the PAR proteins, previously named ASIP, which are indispensable for the establishment of cell pol …
PAR-4: a possible new target for age-related disease.
Qinan W, Ling Z, Bing C. Qinan W, et al. Expert Opin Ther Targets. 2014 Aug;18(8):917-27. doi: 10.1517/14728222.2014.925882. Epub 2014 Jun 3. Expert Opin Ther Targets. 2014. PMID: 24890982 Review.
Recent studies suggest that PAR-4 plays an important role in the progression of many age-related diseases. ...PAR-4 agonists and inhibitors must be identified before gene therapy can commence....
Recent studies suggest that PAR-4 plays an important role in the progression of many age-related diseases. ...PAR-4 agonists a …
PAR(1&2) driven placenta EVT invasion act via LRP5/6 as coreceptors.
Grisaru-Granovsky S, Kumar Nag J, Zakar L, Rudina T, Lal Gupta C, Maoz M, Kozlova D, Bar-Shavit R. Grisaru-Granovsky S, et al. FASEB J. 2020 Dec;34(12):15701-15717. doi: 10.1096/fj.202000306R. Epub 2020 Nov 2. FASEB J. 2020. PMID: 33136328
Immunoprecipitation analyses and protein-protein docking demonstrated the co-association between either PAR(1) or PAR(2) with LRP5/6 forming an axis of PAR-LRP5/6-Axin. Noticeably, in PAR(1) -PAR(2) heterodimers a dominant role is assigned to …
Immunoprecipitation analyses and protein-protein docking demonstrated the co-association between either PAR(1) or PAR(2) with …
Evaluating Earplug Performance over a 2-Hour Work Period with a Fit-Test System.
Gong W, Murphy WJ, Meinke DK, Feng HA, Stephenson MR. Gong W, et al. Semin Hear. 2023 Jun 1;44(4):470-484. doi: 10.1055/s-0043-1769586. eCollection 2023 Nov. Semin Hear. 2023. PMID: 37818150 Free PMC article. Review.
The personal attenuation ratings (PARs) were measured before and after a 2-hour work period while exposed to hazardous noise levels. The minimum acceptable initial PAR was 15 dB. Average decreases in PAR ranged from -0.7 to -2.6 dB across all six earplug types. Sign …
The personal attenuation ratings (PARs) were measured before and after a 2-hour work period while exposed to hazardous noise levels. The min …
Protease-activated receptors: An illustrated review.
Han X, Nieman MT, Kerlin BA. Han X, et al. Res Pract Thromb Haemost. 2020 Dec 6;5(1):17-26. doi: 10.1002/rth2.12454. eCollection 2021 Jan. Res Pract Thromb Haemost. 2020. PMID: 33537526 Free PMC article. Review.
They communicate to cells directly through a special class of G-protein-coupled receptors known as protease-activated receptors (PARs). N-terminal PAR proteolysis unmasks a neo-N-terminus, which serves as a tethered ligand to activate PARs. ...We conclude with portrayal of …
They communicate to cells directly through a special class of G-protein-coupled receptors known as protease-activated receptors (PARs). N-te …
The Enigmatic Function of PARP1: From PARylation Activity to PAR Readers.
Kamaletdinova T, Fanaei-Kahrani Z, Wang ZQ. Kamaletdinova T, et al. Cells. 2019 Dec 12;8(12):1625. doi: 10.3390/cells8121625. Cells. 2019. PMID: 31842403 Free PMC article. Review.
Poly(ADP-ribosyl)ation (PARylation) is catalysed by poly(ADP-ribose) polymerases (PARPs, also known as ARTDs) and then rapidly removed by degrading enzymes. Poly(ADP-ribose) (PAR) is produced from PARylation and provides a delicate and spatiotemporal interaction scaffold f …
Poly(ADP-ribosyl)ation (PARylation) is catalysed by poly(ADP-ribose) polymerases (PARPs, also known as ARTDs) and then rapidly removed by de …
Inhibition of PAR-1 delays aging via activating AMPK in C. elegans.
Wu D, Cai W, Zhang X, Lan J, Zou L, Chen SJ, Wu Z, Chen D. Wu D, et al. Aging (Albany NY). 2020 Nov 20;12(24):25700-25717. doi: 10.18632/aging.104180. Epub 2020 Nov 20. Aging (Albany NY). 2020. PMID: 33232266 Free PMC article.
However, the role of PAR-1 during adulthood remains unknown. Here we show that inhibition of par-1 either by a temperature-sensitive mutant or by RNAi knockdown only during adulthood is sufficient to extend lifespan in C. elegans. ...Additionally, tissue-enriched RN …
However, the role of PAR-1 during adulthood remains unknown. Here we show that inhibition of par-1 either by a temperature-sen …
The PAR-aPKC system: lessons in polarity.
Suzuki A, Ohno S. Suzuki A, et al. J Cell Sci. 2006 Mar 15;119(Pt 6):979-87. doi: 10.1242/jcs.02898. J Cell Sci. 2006. PMID: 16525119 Review.
Ten years ago, par-1 and par-3 were cloned as two of the six par genes essential for the asymmetric division of the Caenorhabditis elegans zygote. PAR-1 is a protein kinase, whereas PAR-3 is a PDZ-domain-containing scaffold protein. ...
Ten years ago, par-1 and par-3 were cloned as two of the six par genes essential for the asymmetric division of the Cae …
6,648 results